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Título
Glucocorticoid Effect in Cancer Patients
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
Methods in molecular biology (Clifton, N.J.)
Cita Bibliográfica
Blanco Nistal, M. M.; Fernández Fernández , J. A. (2023). Glucocorticoid Effect in Cancer Patients. Methods in molecular biology (Clifton, N.J.), 270414
Editorial
Springer
Fecha
2023
ISSN
1064-3745
Resumen
[EN] The use of glucocorticoids is very varied in the context of cancer patients and includes the treatment of
symptoms related to cancer, but also the management of the most common side effects of antitumor
treatments or adverse events related to the immune system. There is a quantity of experimental evidence
demonstrating that cancer cells are immunogenic. However, the effective activation of anticancer T cell
responses closely depends on an efficient antigen presentation carried out by professional antigenpresenting cells such as dendritic cells (DCs). The classic strategies to improve the medical management
of inflammation are aimed at exacerbating the host’s immune response. Although successful in treating a
number of diseases, these drugs have limited efficacy and variable responses can lead to unpredictable
results. The ideal therapy should reduce inflammation without inducing immunosuppression and remains a
challenge for healthcare personnel.
Materia
Palabras clave
Peer review
SI
URI
DOI
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