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Título
Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed.
Part 9: Polymyxins: colistin
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
EFSA Journal
Número de la revista
10
Datos de la obra
Koutsoumanis, Konstantinos, Ana Allende, Ávelino Alvarez Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, and Robert Davies et al. 2021. "Maximum Levels Of Cross‐Contamination For 24 Antimicrobial Active Substances In Non‐Target Feed. Part 9: Polymyxins: Colistin". EFSA Journal 19 (10). doi:10.2903/j.efsa.2021.6861.
Editor
Wiley
Fecha
2021
ISSN
1831-4732
Abstract
[EN] The specific concentrations of colistin in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are
presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC, it was not possible to conclude the assessment until further experimental data become available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels of colistin in feed that showed to have an effect on growth promotion/increased yield
were reported. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these antimicrobials
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