Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease

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Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease

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Título: Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease
Autor: Pisonero-Vaquero, Sandra;Martínez-Ferreras, Ángel;García-Mediavilla, María Victoria;Martínez-Flórez, Susana;Fernández, Ana;Benet, Marta;Olcoz, José Luis;Jover, Ramiro;González-Gallego, Javier;Sánchez-Campos, Sonia
Facultad/Centro: Instituto Universitario de Biomedicina (IBIOMED)
Area de conocimiento: Otros
Resumen: Flavonoids and related compounds seem to have favorable effects on nonalcoholic fatty liver disease (NAFLD) progression, although the exact mechanisms implicated are poorly understood. In this study, we aimed to investigate the effect of the flanovol quercetin on gene expression deregulation involved in the development of NAFLD, as well as the possible implication of phosphatidylinositol 3-kinase (PI3K)/AKT pathway modulation
Descripción física: P. 879-893
Editor: Wiley
Datos: Molecular Nutrition & Food Research, 2015, 59
URI: http://hdl.handle.net/10612/5687
Fecha: 2015-04-22
Tipo: info:eu-repo/semantics/preprint
Materia: Medicina. Salud
Palabras clave: Fatty acid uptake
PI3K/AKT pathway
Lipid metabolism
Flavonoids
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