Differential Behavior Between Isolated and Aggregated Rabbit Auricular Chondrocytes on Plastic Surfaces

DSpace/Manakin Repository

Differential Behavior Between Isolated and Aggregated Rabbit Auricular Chondrocytes on Plastic Surfaces

Show full item record

Title: Differential Behavior Between Isolated and Aggregated Rabbit Auricular Chondrocytes on Plastic Surfaces
Author: Villar-Suárez, V.;Calles-Venal, I.;Bravo, G.;Fernández Álvarez, José Gabriel;Fernández-Caso, M.;Villar-Lacilla, J. M.
xmlui.dri2xhtml.METS-1.0.item-contributor: Facultad de Ciencias Biologicas y Ambientales
xmlui.dri2xhtml.METS-1.0.item-area: Bioquimica y Biologia Molecular
Abstract: A knowledge of the behavior of chondrocytes in culture is relevant for tissue engineering. Chondrocytes dedifferentiate 10 a fibroblast· like phenotype on plastic surfaces. Dedifferentiation is reversible if these cells are then cultured in suspension. In this report a descrip· tion is given of how when chondrocyte aggregates formed in suspension are next seeded on plastic, most of them attach as round or polygonal cells. This morphological differentiation, with synthesis of type II collagen, is stable for long culture periods. This sim· pie method can be of use as a model for studies of chondrocyte behavior on plastic. The results indicate that in addition to culture conditions, such as cell isolation method or cell density, chondrocyte behavior on plastic depends on the presence of aggregates
xmlui.dri2xhtml.METS-1.0.item-desfisica: P. 86-92
xmlui.dri2xhtml.METS-1.0.item-peerreviewed: SI
Publisher: Hindawi Publishing Corporation
xmlui.dri2xhtml.METS-1.0.item-citation: Journal of Biomedicine and Biotechnology, 2004, n. 2
URI: http://hdl.handle.net/10612/6447
Date: 2004-01-23
xmlui.dri2xhtml.METS-1.0.item-tipo: info:eu-repo/semantics/article
Subject: Bioquímica
Biotecnología
xmlui.dri2xhtml.METS-1.0.item-palclave: Auricular Chondrocytes
Plastic Surfaces
Behavior
Rabbits
Exportar referencia a Refworks:


Files in this item

Files Size Format View
Journal of Biomedicine and Biotechnology.pdf 5.394Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record

Search DSpace


Advanced Search

Browse

My Account

Statistics