Study on Viability and Chondrogenic Differentiation of Cryopreserved Adipose Tissue-Derived Mesenchymal stromal Cells for future use in regenerative medicine

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Study on Viability and Chondrogenic Differentiation of Cryopreserved Adipose Tissue-Derived Mesenchymal stromal Cells for future use in regenerative medicine

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dc.contributor Instituto Universitario de Biomedicina (IBIOMED) es_ES
dc.contributor.author López-González, María Elisa
dc.contributor.author Pérez-Castrillo, S.
dc.contributor.author Ordás-Fernández, P.
dc.contributor.author López-González, M.E.
dc.contributor.author Colaço, B.
dc.contributor.author Villar-Suárez, V.
dc.contributor.other Otros es_ES
dc.date 2015-07-23
dc.date.accessioned 2017-07-25T09:59:36Z
dc.date.available 2017-07-25T09:59:36Z
dc.date.issued 2017-07-25
dc.identifier.citation Cryobiology (2015), n. 71 es_ES
dc.identifier.uri http://hdl.handle.net/10612/6449
dc.description P. 256–263 es_ES
dc.description.abstract Adipose-derived mesenchymal stromal cells are promising as a regenerative therapy tool for defective tissues in mesenchymal lineage, including fat, bone, cartilage, and blood vessels. In potential future clinical applications, adipose-derived stem cell cryopreservation is an essential fundamental technology. The aim of this study is to define an adequate protocol for the cryopreservation of adipose-derived mesenchymal stromal cells, by comparing various protocols so as to determine the effects of cryopreservation on viability and chondrogenic differentiation potential of adipose-derived stem cells upon freeze-thawing of AT-MSCs colonies cryopreserved with standard and modified protocols, using flow cytometry and confocal microscopy. The study concludes that adipose-derived mesenchymal stromal cells could be long-term cryopreserved without any loss of their proliferative or differentiation potential es_ES
dc.language spa es_ES
dc.publisher Elsevier es_ES
dc.subject Anatomía es_ES
dc.subject Veterinaria es_ES
dc.subject.other Cryopreservation es_ES
dc.subject.other Crioperservación es_ES
dc.subject.other Chondrogenic differentiation es_ES
dc.subject.other Medicina regenerativa es_ES
dc.title Study on Viability and Chondrogenic Differentiation of Cryopreserved Adipose Tissue-Derived Mesenchymal stromal Cells for future use in regenerative medicine es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.peerreviewed SI es_ES

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