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Título
Intestinal Microbiota Transplantation From HFD-fed and Quercetin Treated Donors Results in a Complex Metabolic Phenotype Transfer that Modulates Obesity-Related NAFLD in Germ Free Mice
Autor
Facultad/Centro
Área de conocimiento
Cita Bibliográfica
Hepatology, 2017, 66 (1), 465A
Editorial
Wiley
Fecha
2017-08-21
Resumen
Intestinal microbiota imbalance and related
gut-liver axis activation have been identified as key mechanisms
in nonalcoholic fatty liver disease (NAFLD) development.
Modulation of intestinal microbiota, through
administration of prebiotics or faecal microbiota transplantation,
is a promising therapeutic approach for obesity
associated diseases including NAFLD. The aim of the
present study is to evaluate the benefits of gut microbiota
transplantation from donors to germ free mice (GFm)
following an experimental treatment with the flavonoid
quercetin in a high fat diet (HFD)-based NAFLD model. Resumen de un trabajo resultado del proyecto de investigación financiado por la Consejería de Educación de la Junta de Castilla y León (referencia LE063U16)
Materia
Palabras clave
Peer review
SI
URI
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