RT info:eu-repo/semantics/article
T1 Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis
A1 Viribay Morales, Aitor
A1 Burgos, José
A1 Fernández Landa, Julen
A1 Seco Calvo, Jesús Ángel
A1 Mielgo Ayuso, Juan Francisco
A2 Fisioterapia
K1 Fisioterapia
K1 Aminoacids
K1 Ergogenic aids
K1 Physical performance
K1 Nitric oxide
K1 Aerobic
K1 Anaerobic
AB [EN] Nitric oxide related ergogenic aids such as arginine (Arg) have shown to impact positively on sport performance through several physiological and metabolic mechanisms. However, research results have shown to be controversial. The great differences regarding required metabolic pathways and physiological demands between aerobic and anaerobic sport disciplines could be the reasons. The aim of this systematic review and meta-analysis was to evaluate the effects of Arg supplementation on aerobic (≤VO2 max) and anaerobic (>VO2 max) performance. Likewise, to show the effective dose and timing of this supplementation. A structured search was carried out in accordance with PRISMA® (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement and PICOS guidelines in PubMed/MEDLINE, Web of Science (WOS), and Scopus databases from inception to January 2020. Eighteen studies were included which compare Arg supplementation with placebo in an identical situation and testing its effects on aerobic and anaerobic performance tests. Trials analyzing supplementation with other supplements were removed and there was not athlete’s level, gender, ethnicity, or age filters. The performed meta-analysis included 15 studies and random effects model and pooled standardized mean differences (SMD) were used according to Hedges’ g. Results revealed that Arg supplementation could improve aerobic (SMD, 0.84; 95% CI, 0.12 to 1.56; magnitude of SMD (MSMD), large; I2, 89%; p = 0.02) and anaerobic (SMD, 0.24; 95% CI, 0.05 to 0.43; MSMD, small; I2, 0%; p = 0.01) performance tests. In conclusion, acute Arg supplementation protocols to improve aerobic and anaerobic performance should be adjusted to 0.15 g/kg of body weight ingested between 60–90 min before. Moreover, chronic Arg supplementation should include 1.5–2 g/day for 4–7 weeks in order to improve aerobic performance, and 10–12 g/day for 8 weeks to enhance anaerobic performance
PB MDPI
LK https://hdl.handle.net/10612/19517
UL https://hdl.handle.net/10612/19517
NO Viribay, A., Burgos, J., Fernández-Landa, J., Seco-Calvo, J., & Mielgo-Ayuso, J. (2020). Effects of arginine supplementation on athletic performance based on energy metabolism: A systematic review and meta-analysis [Review of Effects of arginine supplementation on athletic performance based on energy metabolism: A systematic review and meta-analysis]. Nutrients, 12(5). MDPI AG. https://doi.org/10.3390/NU12051300
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 17-may-2024