TY - JOUR AU - Facultad de Ciencias Biologicas y Ambientales AU - Martínez Burgo, Yolanda AU - Santos Aberturas, Javier AU - Rodríguez García, Antonio AU - García Barreales, Eva AU - Tormo, José Rubén AU - Truman, Andrew W. AU - Reyes, Fernando AU - Aparicio Fernández, Jesús Manuel AU - Liras Padín, Paloma AU - Microbiologia DA - 2019/03/03 UR - https://hdl.handle.net/10612/18075 AB - [EN] Expression of non-native transcriptional activators may be a powerful general method to activate secondary metabolites biosynthetic pathways. PAS-LuxR regulators, whose archetype is PimM, activate the biosynthesis of polyene macrolide antifungals... LA - eng PB - Frontiers Media SA KW - Biotecnología KW - Streptomyces clavuligerus KW - Antibotics biosynthesis regulation KW - PimM KW - Clavulanic acid KW - Cephamycin C KW - Transcriptomics TI - Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis DO - 10.3389/fmicb.2019.00580 T2 - Frontiers in Microbiology VL - 10 M2 - 580 ER -