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Complete genome sequence of ‘Mycobacterium neoaurum’ NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols
dc.contributorFacultad de Ciencias Biologicas y Ambientaleses_ES
dc.contributor.authorRodríguez García, Antonio 
dc.contributor.authorFernández Alegre, Estela
dc.contributor.authorMorales Allende, Alejandro
dc.contributor.authorSola Landa, Alberto
dc.contributor.authorLorraine, Jess
dc.contributor.authorMacdonald, Sandy
dc.contributor.authorDovbnya, Dmitry
dc.contributor.authorSmith, Margaret C. M.
dc.contributor.authorDonova, Marina Viktorovna
dc.contributor.authorBarreiro Méndez, Carlos 
dc.contributor.otherMicrobiologiaes_ES
dc.date2016-04-20
dc.date.accessioned2024-01-16T11:50:14Z
dc.date.available2024-01-16T11:50:14Z
dc.identifier.citationRodríguez-García, A., Fernández-Alegre, E., Morales, A., Sola-Landa, A., Lorraine, J., Macdonald, S., Dovbnya, D., Smith, M. C. M., Donova, M., & Barreiro, C. (2016). Complete genome sequence of “Mycobacterium neoaurum” NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols. Journal of Biotechnology, 224, 64-65. https://doi.org/10.1016/J.JBIOTEC.2016.03.021es_ES
dc.identifier.issn0168-1656
dc.identifier.urihttps://hdl.handle.net/10612/17631
dc.description.abstract[EN] Microbial bioconversion of sterols into high value steroid precursors, such as 4-androstene-3,17-dione (AD), is an industrial challenge. Genes and enzymes involved in sterol degradation have been proposed, although the complete pathway is not yet known. The genome sequencing of the AD producer strain ‘Mycobacterium neoaurum’ NRRL B-3805 (formerly Mycobacterium sp. NRRL B-3805) will serve to elucidate the critical steps for industrial processes and will provide the basis for further genetic engineering. The genome comprises a circular chromosome (5 421 338 bp), is devoid of plasmids and contains 4844 protein-coding geneses_ES
dc.languageenges_ES
dc.publisherElsevieres_ES
dc.subjectBiotecnologíaes_ES
dc.subject.otherMycobacteriumes_ES
dc.subject.otherSteroidses_ES
dc.subject.otherActinobacteriaes_ES
dc.subject.otherGenome sequencees_ES
dc.subject.other4-Androstene-3,17-dionees_ES
dc.subject.otherADes_ES
dc.titleComplete genome sequence of ‘Mycobacterium neoaurum’ NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterolses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1016/j.jbiotec.2016.03.021
dc.description.peerreviewedSIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PCIN-2013-024-C02-01/ES/NUEVOS BIOPROCESOS INDUSTRIALES PARA LA PRODUCCION DE PRECURSORES ESTEROIDEOS DE INTERES INDUSTRIAL A PARTIR DE FITOESTEROLes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.journal.titleJournal of Biotechnologyes_ES
dc.volume.number224es_ES
dc.page.initial64es_ES
dc.page.final65es_ES
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersiones_ES
dc.subject.unesco2415.01 Biología Molecular de Microorganismoses_ES
dc.subject.unesco2414.08 Procesos Microbianoses_ES
dc.description.projectThis work was fully supported by a grant of the European Union program ERA-IB [MySterI (EIB.12.010) through the APCIN call of the Spanish Ministry of Economy and Competitively (MINECO, Spain) (PCIN-2013-024-C02-01)]. Dmitry Dovbnya and Marina Donova acknowledge Russian Science Foundation (Grant No. 14-24-00169) for the supporting of their work. The authors want to thanks the European Union program ERA-IB; the Spanish Ministry of Economy and Competitiveness (MINECO, Spain); the Biotechnology and Biological Sciences Research Council (BBSRC, United Kingdom); the Foundation for Assistance to Small Innovative Enterprises (FASIE, Russia) and the MySterI Consortium (INBIOTEC, Pharmins Ltd., University of York, SINTEF, Technische Universität Dortmund, Gadea Biopharma S.L.).es_ES


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