dc.contributor | Facultad de Ciencias de la Salud | es_ES |
dc.contributor.author | Seco Calvo, Jesús Ángel | |
dc.contributor.author | Vidán Estévez, Julia María | |
dc.contributor.author | Sánchez Herráez, Sergio | |
dc.contributor.other | Fisioterapia | es_ES |
dc.date | 2022-06-20 | |
dc.date.accessioned | 2024-05-27T09:20:42Z | |
dc.date.available | 2024-05-27T09:20:42Z | |
dc.identifier.citation | Seco-Calvo, J., Vidán-Estévez, J. & Sánchez-Herráez, S. Successful healing of non-healing surgical wound based on the release of platelet-derived growth factors from single donor allogeneic platelet-RICH plasma with one freeze-thaw cycle: a case report after a 1-year follow-up. transl med commun 7, 14 (2022). https://doi.org/10.1186/s41231-022-00120-w | es_ES |
dc.identifier.issn | 2396-832X | |
dc.identifier.uri | https://hdl.handle.net/10612/21001 | |
dc.description.abstract | [EN] Background. Non-healing surgical wounds is a risk in certain patients. Recently, allogenic plasma-rich-platelet (PRP) is used such as regenerative treatment of different non-healing surgical wounds. Purpose. We explore the potential role of using platelet-derived growth factors from single donor PRP, with a freeze-thaw process, for the treatment of surgical scar ulcer. Methods. We have used a PRP preparation protocol that involved a single cycle of centrifugation at a mean speed of 2400–2800 rpm of donor blood taken with an apheresis machine. Results. To our knowledge, this is the first study using the platelet-derived growth factors (PDGF) from single donor apheresis, with a freeze-thaw process. Four weeks after daily application of al-PRP, the ulcer progressed satisfactorily; at six weeks, the ulcer had healed. Conclusion. We concluded that the healing of a surgical wound observed in our case, is promising and suggests that al-PRP might play a role in treating surgical scar ulcers. This must be confirmed in future studies. | es_ES |
dc.language | eng | es_ES |
dc.publisher | Springer Nature | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Medicina. Salud | es_ES |
dc.subject.other | Non-healing surgical wound | es_ES |
dc.subject.other | Platelet-derived growth factors (PDGF) | es_ES |
dc.subject.other | Allogenic plasma-rich-platelet (al-PRP) | es_ES |
dc.subject.other | Freeze-thaw process | es_ES |
dc.subject.other | Single donor apheresis | es_ES |
dc.title | Successful healing of non-healing surgical wound based on the release of platelet-derived growth factors from single donor allogeneic platelet-RICH plasma with one freeze-thaw cycle: a case report after a 1-year follow-up | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1186/s41231-022-00120-w | |
dc.description.peerreviewed | SI | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.journal.title | Translational Medicine Communications | es_ES |
dc.volume.number | 7 | es_ES |
dc.issue.number | 14 | es_ES |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |