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Título
Therapeutic effects of psyllium in type 2 diabetic patients
Autor
Facultad/Centro
Área de conocimiento
Datos de la obra
European journal of clinical nutrition, 2002, n. 56
Editor
Nature publishing group
Fecha
2002-06-24
Abstract
The study included three phases: phase 1 (1 week), phase 2 (treatment, 14 g fibre=day, 6 weeks) and phase 3 (4 weeks).
At the end of each phase a clinical evaluation was performed after the ingestion of a test breakfast of 1824.2 kJ (436 kcal).
Measurements included concentrations of blood glucose, insulin, fructosamine, GHbA1c, C-peptide and 24 h urinary glucose
excretion. In addition, uric acid, cholesterol and several mineral and vitamin concentrations were also evaluated.
Twenty type 2 diabetic patients (12 men and 8 women) participated in the study with a mean age of 67.4 y for men
and 66 y for women. The mean body mass index of men was 28.2 kg=m2 and that of women 25.9 kg=m2.
Glucose absorption decreased significantly in the presence of psyllium (12.2%); this reduction is not associated with an
important change in insulin levels (5%). GHbA1c, C-peptide and 24 h urinary glucose excretion decreased (3.8, 14.9 and 22.5%,
respectively) during the treatment with fibre (no significant differences) as well as fructosamine (10.9%, significant differences).
Psyllium also reduced total and LDL cholesterol (7.7 and 9.2%, respectively, significant differences), and uric acid (10%,
significant difference). Minerals and vitamins did not show important changes, except sodium that increased significantly after
psyllium administration.
Materia
Palabras clave
Type 2 diabetic patients
Ispaghula husk
Psyllium
Dietary fiber
Glucose
Insulin
Cholesterol
Capillary blood glucose
Metabolic variables
Ispaghula husk
Psyllium
Dietary fiber
Glucose
Insulin
Cholesterol
Capillary blood glucose
Metabolic variables
Peer review
SI
URI
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