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dc.contributor | Facultad de Veterinaria | es_ES |
dc.contributor.author | Sierra Vega, Matilde | |
dc.contributor.author | García, Juan J. | |
dc.contributor.author | Fernández, Nélida | |
dc.contributor.author | Diez Liébana, María José | |
dc.contributor.author | Calle Pardo, Ángela Pilar | |
dc.contributor.author | Álvarez, Juan C. | |
dc.contributor.author | Carriedo, Demetrio | |
dc.contributor.author | Castro, Luis J. | |
dc.contributor.author | Torre, Mariano de la | |
dc.contributor.author | González, Aranzazu | |
dc.contributor.author | González, M. Angeles | |
dc.contributor.author | Moran, Vicente | |
dc.contributor.author | Prieto, Carlos | |
dc.contributor.author | Sahagún , Ana M. | |
dc.contributor.other | Farmacologia | es_ES |
dc.date | 2002-06-24 | |
dc.identifier.citation | European journal of clinical nutrition, 2002, n. 56 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10612/4448 | |
dc.description | P. 830-842 | es_ES |
dc.description.abstract | The study included three phases: phase 1 (1 week), phase 2 (treatment, 14 g fibre=day, 6 weeks) and phase 3 (4 weeks). At the end of each phase a clinical evaluation was performed after the ingestion of a test breakfast of 1824.2 kJ (436 kcal). Measurements included concentrations of blood glucose, insulin, fructosamine, GHbA1c, C-peptide and 24 h urinary glucose excretion. In addition, uric acid, cholesterol and several mineral and vitamin concentrations were also evaluated. Twenty type 2 diabetic patients (12 men and 8 women) participated in the study with a mean age of 67.4 y for men and 66 y for women. The mean body mass index of men was 28.2 kg=m2 and that of women 25.9 kg=m2. Glucose absorption decreased significantly in the presence of psyllium (12.2%); this reduction is not associated with an important change in insulin levels (5%). GHbA1c, C-peptide and 24 h urinary glucose excretion decreased (3.8, 14.9 and 22.5%, respectively) during the treatment with fibre (no significant differences) as well as fructosamine (10.9%, significant differences). Psyllium also reduced total and LDL cholesterol (7.7 and 9.2%, respectively, significant differences), and uric acid (10%, significant difference). Minerals and vitamins did not show important changes, except sodium that increased significantly after psyllium administration. | es_ES |
dc.language | eng | es_ES |
dc.publisher | Nature publishing group | es_ES |
dc.subject | Ecología. Medio ambiente | es_ES |
dc.subject | Farmacología | es_ES |
dc.subject | Zoología | es_ES |
dc.subject.other | Type 2 diabetic patients | es_ES |
dc.subject.other | Ispaghula husk | es_ES |
dc.subject.other | Psyllium | es_ES |
dc.subject.other | Dietary fiber | es_ES |
dc.subject.other | Glucose | es_ES |
dc.subject.other | Insulin | es_ES |
dc.subject.other | Cholesterol | es_ES |
dc.subject.other | Capillary blood glucose | es_ES |
dc.subject.other | Metabolic variables | es_ES |
dc.title | Therapeutic effects of psyllium in type 2 diabetic patients | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.description.peerreviewed | SI | es_ES |
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