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dc.contributorFacultad de Veterinariaes_ES
dc.contributor.authorGonzález, Aranzazu
dc.contributor.authorFernández, Nélida
dc.contributor.authorSahagún , Ana M. 
dc.contributor.authorDiez Liébana, María José 
dc.contributor.authorSierra Vega, Matilde 
dc.contributor.authorGarcía, Juan J.
dc.contributor.otherFarmacologiaes_ES
dc.date2009-06-10
dc.identifier.citationCurrent Drug Metabolism, 2009, n.10es_ES
dc.identifier.urihttp://hdl.handle.net/10612/4533
dc.descriptionP. 359-368es_ES
dc.description.abstractAbstract: The antiparasitic activity of ivermectin depends 011 the presence of an active drug concentration at the site of parasites location for an adapted length of time. lvermectin interactions with another concurrently administered drug can occur. Concomitant administration of sorne drugs can increase the bioavailability of simultaneously administered ivermectin. This can, in sorne cases, become a useful pharmacological strategy to improve its antiparasitic efficacy and to delay the development of resistance in livestock or, in other cases, lead to adverse drug reactions and toxicities. On the other hand, other interactions can result in lower levels of this drug, determining that moderate resistant residual populations of the parasites may persist to contarninate pastures. The characterisation of ivermectin interac­ tions can be used to predict and optimisc the valúe of the parasiticide effects. This article reviews the pharmacological interactions of ivermectin in several domestic animal species.es_ES
dc.languageenges_ES
dc.publisherBentham Science Publisherses_ES
dc.subjectEcología. Medio ambientees_ES
dc.subjectFarmacologíaes_ES
dc.subjectZoologíaes_ES
dc.subject.otherIvermectines_ES
dc.subject.otherPharmacokinetic interactionses_ES
dc.subject.otherPharmacodynamic interactionses_ES
dc.subject.otherVeterinaryes_ES
dc.titleA Review of the Pharmacological lnteractions of Ivermectin in Several Animal Specieses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.peerreviewedSIes_ES


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