Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease

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Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease

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Title: Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of non-alcoholic fatty liver disease
Author: Pisonero-Vaquero, Sandra;Martínez Ferreras, Ángel;García-Mediavilla, María Victoria;Martínez-Flórez, Susana;Fernández, Ana;Benet, Marta;Olcoz, José Luis;Jover, Ramiro;González-Gallego, Javier;Sánchez-Campos, Sonia
xmlui.dri2xhtml.METS-1.0.item-contributor: Instituto Universitario de Biomedicina (IBIOMED)
xmlui.dri2xhtml.METS-1.0.item-area: Otros
Abstract: Flavonoids and related compounds seem to have favorable effects on nonalcoholic fatty liver disease (NAFLD) progression, although the exact mechanisms implicated are poorly understood. In this study, we aimed to investigate the effect of the flanovol quercetin on gene expression deregulation involved in the development of NAFLD, as well as the possible implication of phosphatidylinositol 3-kinase (PI3K)/AKT pathway modulation
xmlui.dri2xhtml.METS-1.0.item-desfisica: P. 879-893
Publisher: Wiley
xmlui.dri2xhtml.METS-1.0.item-citation: Molecular Nutrition & Food Research, 2015, 59
URI: http://hdl.handle.net/10612/5687
Date: 2015-04-22
xmlui.dri2xhtml.METS-1.0.item-tipo: info:eu-repo/semantics/preprint
Subject: Medicina. Salud
xmlui.dri2xhtml.METS-1.0.item-palclave: Fatty acid uptake
PI3K/AKT pathway
Lipid metabolism
Flavonoids
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