• español
  • English
  • français
  • Deutsch
  • português (Brasil)
  • italiano
Consorcio BUCLE Recolector
  • Contact Us
  • Send Feedback
  • Enlaces y accesos
    • Derechos de autor
    • Políticas
    • Guía de autoarchivo
    • FAQ y ayuda
    • La ULE y el Acceso Abierto
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Repositorio
    Institucional
    Abierto

    Consorcio BUCLE Recolector

    Browse

    All of BULERIACommunities and CollectionsAuthorsDirectoresTitlesSubjectsFacultad/CentroÁrea de conocimientoFecha de creación/publicaciónTitulaciónThis CollectionAuthorsDirectoresTitlesSubjectsFacultad/CentroÁrea de conocimientoFecha de creación/publicaciónTitulación

    My Account

    Login

    Statistics

    View Usage Statistics

    Otros enlaces

    View Item 
    •   BULERIA Home
    • Scientific Production
    • Untitled
    • View Item
    •   BULERIA Home
    • Scientific Production
    • Untitled
    • View Item

    Compartir

    Export

    RISMendeleyRefworksZotero
    • edm
    • marc
    • xoai
    • qdc
    • ore
    • ese
    • dim
    • uketd_dc
    • oai_dc
    • etdms
    • rdf
    • mods
    • mets
    • didl
    • premis

    Citas

    Título
    Molecular characterization of Haemophilus parasuis ferric hydroxamate uptake (fhu) genes and constitutive expression of the FhuA receptor
    Autor
    Río González, Mª Luisa delAutoridad Buleria
    Navas, Jesús
    Martín, Ana Judith
    Gutiérrez Martín, César BernardoAutoridad BuleriaORCID
    Rodríguez-Barbosa, José Ignacio
    Rodríguez Ferri, Elías FernandoAutoridad BuleriaORCID
    Facultad/Centro
    Facultad de Veterinaria
    Área de conocimiento
    Sanidad Animal
    Datos de la obra
    Veterinary Research, 2006, vol. 37
    Editor
    BioMed Central
    Fecha
    2006-10-23
    Abstract
    Bacteria have evolved a set of highly specialized proteins to capture iron in irondepleted environments. The acquisition and uptake of iron present in the extracellular milieu of eukaryotic organisms is indispensable for the growth and survival of microbial pathogens in the course of infection. Haemophilus parasuis is the causative agent of Glässer disease, which is responsible for considerable financial losses in pig-rearing worldwide. To gain insight into the mechanisms involved in siderophore-mediated iron uptake in H. parasuis, genes in the H. parasuis ferric hydroxamate uptake (Fhu) region were amplified in the work being reported here. As has been described in A. pleuropneumoniae, an Fhu genomic region was also present in H. parasuis, being composed of four potential consecutive open reading frames (ORF) designated as fhuC, fhuD, fhuB, and fhuA, respectively. By immunoblotting, using a cross-reactive polyclonal antibody raised against Actinobacillus pleuropneumoniae FhuA protein, it was demonstrated that this protein was constitutively expressed in H. parasuis and its level of expression was not modified under conditions of restricted iron availability. This is the first report describing the presence of the fhu genes in H. parasuis. Our results indicate that FhuA protein expression is not affected under ironrestricted conditions, however, it is one of the targets of the humoral immune response
    Materia
    Sanidad animal
    Veterinaria
    Palabras clave
    Haemophilus parasuis
    Ferric hydroxamate uptake
    Iron
    Peer review
    SI
    URI
    http://hdl.handle.net/10612/6686
    Collections
    • Untitled [2723]
    Show full item record
    Files in this item
    Nombre:
    Vet. Res.pdf
    Tamaño:
    252.8Kb
    Formato:
    Adobe PDF
    Thumbnail
    FilesOpen