2024-03-29T06:12:33Zhttp://buleria.unileon.es/oai/requestoai:buleria.unileon.es:10612/45272020-12-10T09:00:58Zcom_10612_17col_10612_18
The pharmacokinetics and metabolism of ivermectin in domestic animal species
González, Aranzazu
Sahagún, Ana M.
Diez, M. José
Fernández, Nélida
Sierra, Matilde
García, Juan J.
Farmacologia
Ecología. Medio ambiente
Farmacología
Zoología
P. 25-37
The pharmacokinetic properties of drugs are closely related to their pharmacological efficacy. The kinetics of ivermectin are characterised,
in general terms, by a slow absorption process, a broad distribution in the organism, low metabolism, and slow excretion. The
kinetics vary according to the route of administration, formulation, animal species, body condition, age, and physiological status, all of
which contribute to differences in drug efficacy. Characterisation of ivermectin kinetics can be used to predict and optimise the value of
the parasiticide effects and to design programmes for parasite control. This article reviews the pharmacokinetics of ivermectin in several
domestic animal species.
2015-08-19
2015-08-19
2015-08-19
info:eu-repo/semantics/article
The Veterinary Journal, 2009, n. 179
http://hdl.handle.net/10612/4527
Elsevier