RT info:eu-repo/semantics/article T1 Determining the severity of Parkinson’s disease in patients using a multi task neural network A1 García Ordás, María Teresa A1 Benítez Andrades, José Alberto A1 Aveleira Mata, José Antonio A1 Alija Pérez, José Manuel A1 Benavides Cuéllar, María del Carmen A2 Lenguajes y Sistemas Informaticos K1 Ingeniería de sistemas K1 Parkinson K1 Deep learning K1 Autoencoder K1 Disease progress K1 Mixed model K1 Classification K1 Regression AB [EN] Parkinson’s disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of life of both the patients and their families and it is also the second most prevalent neurodegenerative disorder after Alzheimer in people over the age of 60. Most current studies on the prediction of Parkinson’s severity are carried out in advanced stages of the disease. In this work, the study analyzes a set of variables that can be easily extracted from voice analysis, making it a very non-intrusive technique. In this paper, a method based on different deep learning techniques is proposed with two purposes. On the one hand, to find out if a person has severe or non-severe Parkinson’s disease, and on the other hand, to determine by means of regression techniques the degree of evolution of the disease in a given patient. The UPDRS (Unified Parkinson’s Disease Rating Scale) has been used by taking into account both the motor and total labels, and the best results have been obtained using a mixed multi-layer perceptron (MLP) that classifies and regresses at the same time and the most important features of the data obtained are taken as input, using an autoencoder. A success rate of 99.15% has been achieved in the problem of predicting whether a person suffers from severe Parkinson’s disease or non-severe Parkinson’s disease. In the degree of disease involvement prediction problem case, a MSE (Mean Squared Error) of 0.15 has been obtained. Using a full deep learning pipeline for data preprocessing and classification has proven to be very promising in the field Parkinson’s outperforming the state-of-the-art proposals. PB Springer SN 1380-7501 LK http://hdl.handle.net/10612/16677 UL http://hdl.handle.net/10612/16677 NO García-Ordás, M. T., Benítez-Andrades, J. A., Aveleira-Mata, J., Alija-Pérez, J.-M., & Benavides, C. (2023). Determining the severity of Parkinson’s disease in patients using a multi task neural network. Multimedia Tools and Applications. https://doi.org/10.1007/s11042-023-14932-x DS BULERIA. Repositorio Institucional de la Universidad de León RD 28-abr-2024