RT info:eu-repo/semantics/article
T1 Antimicrobial-resistant Enterobacter cloacae complex strains isolated from fresh vegetables intended for raw consumption and their farm environments in the Northwest of Spain
A1 Pintor-Cora, Alberto
A1 Alegría, Ángel
A1 Ramos-Vivas, Jose
A1 García López, María Luisa
A1 Santos Buelga, Jesús Ángel
A1 Rodríguez Calleja, José María
A2 Nutricion y Bromatologia
K1 Tecnología de los alimentos
K1 Antimicrobial resistance
K1 Enterobacter cloacae complex
K1 Colistin resistance
K1 Fresh produce
K1 AmpC
AB [EN] Antimicrobial resistance is a global concern with significant public health implications. We investigated the roleof fresh vegetables and their cultivation environments as reservoirs for antimicrobial-resistant Enterobactercloacae complex (ECC) strains. The study focused on AmpC-producing ECC isolates and their resistance tocolistin, a last resort antibiotic.AmpC-producing ECC isolates were detected and confirmed in 10.2% of the 235 samples examined, with nosignificant difference (p > 0.05) in prevalence between farm and street market samples. Further analysis of 24AmpC-ECC isolates revealed that 16.7% exhibited resistance to colistin.A colistin-resistant E. kobei strain (AG07E) was detected in irrigation water from a vegetable farm for the firsttime in Spain. This strain carried the mcr-9.1 gene, demonstrating transferability. It was included in ST56 whichis predominantly reported in clinical E. kobei harbouring the mcr-9 gene. Additionally, we identified a multidrugresistantE. kobei strain (ZA03E) from carrot samples, exhibiting colistin resistance and potential human pathogenicity.This strain belonged to ST125 which has clonal relationships with strains in ST56.Our findings emphasise the importance of monitoring and addressing antimicrobial-resistant ECC strains infresh vegetables and their production environments, particularly the water, to mitigate potential risks to publichealth from a One Health perspective.
PB Elsevier
SN 0023-6438
LK https://hdl.handle.net/10612/17324
UL https://hdl.handle.net/10612/17324
NO Pintor-Cora, A., Alegría, Á., Ramos-Vivas, J., García-López, M. L., Santos, J. A., & Rodríguez-Calleja, J. M. (2023). Antimicrobial-resistant Enterobacter cloacae complex strains isolated from fresh vegetables intended for raw consumption and their farm environments in the Northwest of Spain. LWT, 188, 115382.
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 12-jun-2024