RT info:eu-repo/semantics/article T1 Complete genome sequence of ‘Mycobacterium neoaurum’ NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols A1 Rodríguez García, Antonio A1 Fernández Alegre, Estela A1 Morales Allende, Alejandro A1 Sola Landa, Alberto A1 Lorraine, Jess A1 Macdonald, Sandy A1 Dovbnya, Dmitry A1 Smith, Margaret C. M. A1 Donova, Marina Viktorovna A1 Barreiro Méndez, Carlos A2 Microbiologia K1 Biotecnología K1 Mycobacterium K1 Steroids K1 Actinobacteria K1 Genome sequence K1 4-Androstene-3,17-dione K1 AD K1 2415.01 Biología Molecular de Microorganismos K1 2414.08 Procesos Microbianos AB [EN] Microbial bioconversion of sterols into high value steroid precursors, such as 4-androstene-3,17-dione (AD), is an industrial challenge. Genes and enzymes involved in sterol degradation have been proposed, although the complete pathway is not yet known. The genome sequencing of the AD producer strain ‘Mycobacterium neoaurum’ NRRL B-3805 (formerly Mycobacterium sp. NRRL B-3805) will serve to elucidate the critical steps for industrial processes and will provide the basis for further genetic engineering. The genome comprises a circular chromosome (5 421 338 bp), is devoid of plasmids and contains 4844 protein-coding genes PB Elsevier SN 0168-1656 LK https://hdl.handle.net/10612/17631 UL https://hdl.handle.net/10612/17631 NO Rodríguez-García, A., Fernández-Alegre, E., Morales, A., Sola-Landa, A., Lorraine, J., Macdonald, S., Dovbnya, D., Smith, M. C. M., Donova, M., & Barreiro, C. (2016). Complete genome sequence of “Mycobacterium neoaurum” NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols. Journal of Biotechnology, 224, 64-65. https://doi.org/10.1016/J.JBIOTEC.2016.03.021 DS BULERIA. Repositorio Institucional de la Universidad de León RD 21-may-2024