RT info:eu-repo/semantics/article T1 Drug-related problems and polypharmacy in nursing home residents: a cross-sectional study A1 Díez Láiz, Raquel A1 Cadenas, Raquel A1 Susperregui Lesaca, Julián A1 Sahagún Prieto, Ana María A1 Fernández Martínez, María Nélida A1 García Viéitez, Juan José A1 Sierra Vega, Matilde A1 López Cadenas, Cristina A2 Farmacologia K1 Farmacología K1 Veterinaria K1 drug-drug interactions K1 drug-related problems K1 elderly K1 medication K1 nursing home K1 polypharmacy K1 32 Ciencias Médicas K1 3209 Farmacología K1 3209.03 Evaluación de Medicamentos AB [EN] At present, 19.2% of the Spanish population is aged 65 or older. Polypharmacy is a frequent condition among the elderly, especially in those living in nursing homes, which is associated with adverse outcomes, such as adverse drug events or drug-drug interactions. This study aimed to assess the pattern of polypharmacy in a nursing home in León, one of Spain’s most ageing regions, and its relationship with different drug-related problems. A descriptive, observational, and crosssectional study design was used; 222 residents were involved in this study. Data on drug use were collected from medical charts. Information was screened with the software CheckTheMeds, BOT PLUS and Drug-Reax. Residents were on a median of 7 medicines. Polypharmacy and inappropriate medications were present in 78.8% and 96.8% of residents, respectively. Drug-related problems were present in almost all the populations evaluated. Drug-drug interactions were very common in participants (81.1%), being severe/moderate in 24.7%. A high prevalence of polypharmacy and drugrelated problems in the nursing home population assessed has been observed. A significantly higher risk of suffering drug-drug interactions was revealed for increasing polypharmacy and anticholinergic risk. A regular evaluation of drug prescribing in nursing home residents is necessary to minimize drug-related problems risk. PB MDPI SN 1661-7827 LK https://hdl.handle.net/10612/17763 UL https://hdl.handle.net/10612/17763 NO .Díez, R., Cadenas, R., Susperregui, J., Sahagún, A. M., Fernández, N., García, J. J., Sierra, M., & López, C. (2022). Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study. International Journal of Environmental Research and Public Health, 19(7). https://doi.org/10.3390/IJERPH19074313 DS BULERIA. Repositorio Institucional de la Universidad de León RD 30-jun-2024