RT info:eu-repo/semantics/article
T1 Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination
A1 Mauriz García, Elba
A1 Fernández Vázquez, José P.
A1 Díez Flecha, C.
A1 Reguero Celada, S.
A1 Fernández Villa, Tania
A1 Fernández-Somoano, A.
A1 Caylà, J.A.
A1 Lozano García, J.A.
A1 Vázquez Casares, Ana María
A1 Martín Sánchez, Vicente
A2 Enfermeria
K1 Enfermería
K1 Initial vaccination
K1 Elderly care home
K1 Pre-existing medical conditions
K1 Nursing home
K1 Vaccination coverage
K1 3212 Salud Publica
K1 3202 Epidemiología
K1 3205 Medicina Interna
AB [EN] Elderly care home residents are particularly vulnerable to COVID-19 due to immunesenescence, pre-existing medical conditions, and the risk of transmission from staff and visitors.This study aimed to describe the outcomes of a COVID-19 outbreak in a long-term care facilityfor elderly persons following the initial vaccination. A single-center, retrospective, observationaldesign was used to analyze the variables associated with hospitalization and death rate by logisticregression. Adjusted odds ratios (aOR) and their 95% confidence intervals (CI) were calculated.Sixty-eight residents received the first dose of the COVID-19 vaccine. Despite being negative six daysafter vaccination, the performance of a second test 4 days later revealed 51 positives (75.0%) amongresidents and 18 among workers (56.3%). A total of 65 of the 68 residents (95.58%) had positiveresults with symptoms, whereas 34.9% required hospitalization, and 25.8% died. The best-fittingmodel to explain the distribution of cases reflects three points at the time of infection.. The timefrom vaccination to symptom onset explains the hospitalization and mortality rates since a dayelapsed halves the risk of hospitalization (aOR = 0.57; CI = 0.38−0.75) and the risk of death by aquarter (aOR = 0.74; CI = 0.63−0.88). Nursing homes present an elevated risk of transmission andseverity of SARS-CoV-2 infection. Although vaccination reduces the risk of hospitalization anddeath, extreme prevention and control measures are essential in these institutions despite the highvaccination coverage.
PB MDPI
SN 2076-393X
LK https://hdl.handle.net/10612/17888
UL https://hdl.handle.net/10612/17888
NO Mauriz, E., Fernández-Vázquez, J. P., Díez-Flecha, C., Reguero-Celada, S., Fernández-Villa, T., Fernández-Somoano, A., Caylà, J. A., Lozano-García, J. A., Vázquez-Casares, A. M., & Martín-Sánchez, V. (2023). Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination. Vaccines, 11(8). https://doi.org/10.3390/VACCINES11081382
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 17-may-2024