RT info:eu-repo/semantics/article
T1 Regenerative Medicine Applied to Musculoskeletal Diseases in Equines: A Systematic Review
A1 Pérez Fraile, Andrea
A1 González Cubero, Elsa
A1 Martínez Flórez, Susana
A1 Rodríguez Olivera, Elías
A1 Villar Suárez, María Vega
A2 Medicina y Cirugia Animal
K1 Veterinaria
K1 Horse
K1 Osteoarthritis
K1 Musculoskeletal disease
K1 Regenerative therapy
K1 Mesenchymal stem cells
K1 3109 Ciencias Veterinarias
AB [EN] Musculoskeletal injuries in horses have a great economic impact, predominantly affecting tendons, ligaments, and cartilage, which have limited natural regeneration. Cell therapy, which uses mesenchymal stem cells due to their tissue differentiation properties and anti-inflammatory and immunoregulatory effects, aims to restore damaged tissue. In this manuscript, we performed a systematic review using the Parsifal tool, searching the PubMed and Web of Science databases for articles on regenerative medicine for equine musculoskeletal injuries. Our review covers 17 experimental clinical studies categorized by the therapeutic approach used: platelet-rich plasma, conditioned autologous serum, mesenchymal stem cells, and secretome. These therapies reduce healing time, promote regeneration of fibrocartilaginous tissue, improve cellular organization, and improve joint functionality and sustainability. In conclusion, regenerative therapies using platelet-rich plasma, conditioned autologous serum, equine mesenchymal stem cells, and the emerging field of the secretome represent a promising and highly effective approach for the treatment of joint pathologies in horses, implying a valuable advance in equine healthcare.
PB MDPI
LK https://hdl.handle.net/10612/18468
UL https://hdl.handle.net/10612/18468
NO Pérez Fraile, A., González-Cubero, E., Martínez-Flórez, S., Olivera, E. R., & Villar-Suárez, V. (2023). Regenerative Medicine Applied to Musculoskeletal Diseases in Equines: A Systematic Review [Review of Regenerative Medicine Applied to Musculoskeletal Diseases in Equines: A Systematic Review]. Veterinary Sciences, 10(12). Multidisciplinary Digital Publishing Institute (MDPI). https://doi.org/10.3390/VETSCI10120666
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 17-jun-2024