RT info:eu-repo/semantics/article T1 In vitro activity of essential oils against microbial isolates from otitis externa cases in dogs A1 Gómez García, Manuel A1 Madrigal, Irene A1 Puente Fernández, Héctor A1 Mencía Ares, Óscar A1 Argüello Rodríguez, Héctor A1 Carvajal Urueña, Ana María A1 Fregeneda Grandes, Juan Miguel A2 Sanidad Animal K1 Veterinaria K1 Essential oils K1 Minimum inhibitory concentration K1 Minimum bactericidal concentration K1 Minimum fungicidal concentration K1 Otitis externa K1 Dogs K1 3109 Ciencias Veterinarias AB [EN] Despite the number of studies focused on the potential use of essential oils (EOs) as an alternative to conventional treatments of canine external otitis, there is controversy about their antimicrobial activity which could be explained by differences in technical or biological aspects. This study focuses on the antimicrobial activity of three single EO compounds (thymol, cinnamaldehyde and carvacrol) and two EOs (clove and oregano) against clinical isolates recovered from canine otitis externa cases (14 bacterial isolates belonging to five different genera and six Malassezia pachydermatis isolates). All compounds showed activity and cinnamaldehyde exhibited the highest bactericidal and fungicidal activity. The susceptibility was lower among bacterial isolates than fungal isolates, being this difference more evident for Gram-positive bacteria. No relationship between antibiotic multi-resistant profile and susceptibility to compounds was observed. To sum up, our results provide appropriate information about appropriate concentrations of promising candidates for the topic treatment of canine otitis. PB Taylor & Francis Online SN 1478-6419 LK https://hdl.handle.net/10612/19355 UL https://hdl.handle.net/10612/19355 NO Gómez-García, M., Madrigal, I., Puente, H., Mencía-Ares, Ó., Argüello, H., Carvajal, A., & Fregeneda-Grandes, J. M. (2022). In vitro activity of essential oils against microbial isolates from otitis externa cases in dogs. Natural Product Research, 36(17), 4552-4556. https://doi.org/10.1080/14786419.2021.1993217 DS BULERIA. Repositorio Institucional de la Universidad de León RD Jul 12, 2024