RT info:eu-repo/semantics/article
T1 The Role of Selenium Mineral Trace Element in Exercise: Antioxidant Defense System, Muscle Performance, Hormone Response, and Athletic Performance. A Systematic Review
A1 Fernández Lázaro, Diego
A1 Fernández Lázaro, César Ignacio
A1 Mielgo Ayuso, Juan
A1 Jiménez Lavascués, Lourdes
A1 Córdoba Martínez, Alfredo
A1 Seco Calvo, Jesús Ángel
A2 Fisioterapia
K1 Fisioterapia
K1 Mineral trace element
K1 Selenium
K1 Exercise
K1 Antioxidants
K1 Muscle
K1 Hormone response
K1 Athletic performance
AB [EN] Exercise overproduces oxygen reactive species (ROS) and eventually exceeds the body’s antioxidant capacity to neutralize them. The ROS produce damaging effects on the cell membrane and contribute to skeletal muscle damage. Selenium (Se), a natural mineral trace element, is an essential component of selenoproteins that plays an important role in antioxidant defense. The activity of the enzyme glutathione peroxidase (GPx), a highly-efficient antioxidant enzyme, is closely dependent on the presence of Se. These properties of Se may be potentially applicable to improve athletic performance and training recovery. We systematically searched for published studies to evaluate the effectiveness of Se supplementation on antioxidant defense system, muscle performance, hormone response, and athletic performance among physically active individuals. We used the Preferred Reporting Elements for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and searched in SCOPUS, Web of Science (WOS), and PubMed databases to identify published studies until March 2020. The systematic review incorporated original studies with randomized controlled crossover or parallel design in which intake of Se administered once a day was compared with the same placebo conditions. No exclusions were applied for the type of physical exercise performed, the sex, nor the age of the participants. Among 150 articles identified in the search, 6 met the criteria and were included in the systematic review. The methodological quality of the studies was evaluated using the McMaster Critical Review Form. Oral Se supplementation with 180 µg/day or 240 µg/day (selenomethionine) and 200 µg/day (Sodium Selenite), significantly decreased lipid hydroperoxide levels and increased GPx in plasma, erythrocyte, and muscle. No significant effects were observed on athletic performance, testosterone hormone levels, creatine kinase activity, and exercise training-induced adaptations on oxidative enzyme activities or on muscle fiber type myosin heavy chain expression. In addition, Se supplementation showed to have a dampening effect on the mitochondria changes in chronic and acute exercise. In summary, the use of Se supplementation has no benefits on aerobic or anaerobic athletic performance but it may prevent Se deficiencies among athletes with high-intensity and high-volume training. Optimal Se plasma levels may be important to minimize chronic exercise-induced oxidative effects and modulate the exercise effect on mitochondrial changes.
PB MDPI
LK https://hdl.handle.net/10612/19563
UL https://hdl.handle.net/10612/19563
NO Fernández Lázaro, D., Fernandez Lazaro, C. I., Mielgo Ayuso, J., Navascués, L. J., Córdova Martínez, A. y Seco Calvo, J. (2020) The Role of Selenium Mineral Trace Element in Exercise: Antioxidant Defense System, Muscle Performance, Hormone Response, and Athletic Performance. A Systematic Review. Nutrients, 12, 1790. https://doi.org/10.3390/nu12061790
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 13-jun-2024