RT info:eu-repo/semantics/article
T1 Therapeutic effects of psyllium in type 2 diabetic patients
A1 Sierra Vega, Matilde
A1 García, Juan J.
A1 Fernández, Nélida
A1 Diez Liébana, María José
A1 Calle Pardo, Ángela Pilar
A1 Álvarez, Juan C.
A1 Carriedo, Demetrio
A1 Castro, Luis J.
A1 Torre, Mariano de la
A1 González, Aranzazu
A1 González, M. Angeles
A1 Moran, Vicente
A1 Prieto, Carlos
A1 Sahagún , Ana M.
A2 Farmacologia
K1 Ecología. Medio ambiente
K1 Farmacología
K1 Zoología
K1 Type 2 diabetic patients
K1 Ispaghula husk
K1 Psyllium
K1 Dietary fiber
K1 Glucose
K1 Insulin
K1 Cholesterol
K1 Capillary blood glucose
K1 Metabolic variables
AB The study included three phases: phase 1 (1 week), phase 2 (treatment, 14 g fibre=day, 6 weeks) and phase 3 (4 weeks).At the end of each phase a clinical evaluation was performed after the ingestion of a test breakfast of 1824.2 kJ (436 kcal).Measurements included concentrations of blood glucose, insulin, fructosamine, GHbA1c, C-peptide and 24 h urinary glucoseexcretion. In addition, uric acid, cholesterol and several mineral and vitamin concentrations were also evaluated.Twenty type 2 diabetic patients (12 men and 8 women) participated in the study with a mean age of 67.4 y for menand 66 y for women. The mean body mass index of men was 28.2 kg=m2 and that of women 25.9 kg=m2.Glucose absorption decreased significantly in the presence of psyllium (12.2%); this reduction is not associated with animportant change in insulin levels (5%). GHbA1c, C-peptide and 24 h urinary glucose excretion decreased (3.8, 14.9 and 22.5%,respectively) during the treatment with fibre (no significant differences) as well as fructosamine (10.9%, significant differences).Psyllium also reduced total and LDL cholesterol (7.7 and 9.2%, respectively, significant differences), and uric acid (10%,significant difference). Minerals and vitamins did not show important changes, except sodium that increased significantly afterpsyllium administration.
PB Nature publishing group
LK http://hdl.handle.net/10612/4448
UL http://hdl.handle.net/10612/4448
NO European journal of clinical nutrition, 2002, n. 56
NO P. 830-842
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 20-abr-2024