RT info:eu-repo/semantics/article T1 Detection and replication of QTL underlying resistance to gastrointestinal nematodes in adult sheep using the ovine 50K SNP array A1 Atlija, Marina A1 Arranz Santos, Juan José A1 Martínez Valladares, María A1 Gutiérrez Gil, Beatriz A2 Producción Animal K1 Producción animal K1 Nematodos K1 Ganado ovino K1 Gastrointestinal nematodes AB Persistence of gastrointestinal nematode (GIN) infection and the related control methods have major impacts on the sheep industry worldwide. Based on the information generated with the Illumina OvineSNP50 BeadChip (50K chip), this study aims at confirming quantitative trait loci (QTL) that were previously identified by microsatellite‑based genome scans and identifying new QTL and allelic variants that are associated with indicator traits of parasite resistance in adult sheep. We used a commercial half‑sib population of 518 Spanish Churra ewes with available data for fecal egg counts (FEC) and serum levels of immunoglobulin A (IgA) to perform different genome scan QTL mapping analyses based on classical linkage analysis (LA), a combined linkage disequilibrium and linkage analysis (LDLA) and a genome‑wide association study (GWAS) PB Institut National de la Recherche Agronomique (INRA) YR 2016 FD 2016-01-27 LK http://hdl.handle.net/10612/5017 UL http://hdl.handle.net/10612/5017 NO Genetics Selection Evolution, 2016, vol. 48, n. 4 NO 16 p. NO This work was supportedby a competitive grant from the Castilla and León regional government (Juntade Castilla y León) (Ref. LE245A12-2) and the AGL2012-34437 project fundedby the Spanish Ministry of Economy and Competitiveness (MINECO). M Atlijais a grateful grantee of a Marie Curie fellowship funded by the EC-fundedInitial Training Network (ITN) NematodeSystemHealth (FP7-PEOPLE-2010-ITNRef. 264639). B Gutiérrez-Gil is funded through the Spanish “Ramón y Cajal”Programme (RYC-2012-10230) from the MINECO. DS BULERIA. Repositorio Institucional de la Universidad de León RD 19-abr-2024