RT info:eu-repo/semantics/article
T1 Differential Behavior Between Isolated and Aggregated Rabbit Auricular Chondrocytes on Plastic Surfaces
A1 Villar Suárez, María Vega
A1 Calles-Venal, I.
A1 Bravo, G.
A1 Fernández Álvarez, José Gabriel
A1 Fernández-Caso, M.
A1 Villar-Lacilla, José María
A2 Bioquimica y Biologia Molecular
K1 Bioquímica
K1 Biotecnología
K1 Auricular  Chondrocytes
K1 Plastic Surfaces
K1 Behavior
K1 Rabbits
AB A knowledge of the behavior of chondrocytes in culture is relevant for tissue engineering. Chondrocytes dedifferentiate 10 a fibroblast· like phenotype on plastic surfaces. Dedifferentiation is reversible if these cells are then cultured in suspension. In this report a descrip· tion is given of how when chondrocyte aggregates formed in suspension are next seeded on plastic, most of them attach as round or polygonal cells. This morphological differentiation, with synthesis of type II collagen, is stable for long culture periods. This sim· pie method can be of use as a model for studies of chondrocyte behavior on plastic. The results indicate that in addition to culture conditions, such as cell isolation method or cell density, chondrocyte behavior on plastic depends on the presence of aggregates
PB Hindawi Publishing Corporation
YR 2017
FD 2017-07-19
LK http://hdl.handle.net/10612/6447
UL http://hdl.handle.net/10612/6447
NO Journal of Biomedicine and Biotechnology, 2004, n. 2
NO P. 86-92
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 26-abr-2024