RT info:eu-repo/semantics/article T1 Changes in antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolated from pigs in Spain during the last decade A1 Gutiérrez Martín, César Bernardo A1 García del Blanco, Noemí A1 Blanco, Mónica A1 Navas, Jesús A1 Rodríguez Ferri, Elías Fernando A2 Sanidad Animal K1 Sanidad animal K1 Veterinaria K1 Actinobacillus pleuropneumoniae K1 Pleuropneumonia K1 Antimicrobial susceptibility K1 Clinical Isolates K1 Ganado porcino K1 España AB A total of 229 Spanish Actinobacillus pleuropneumoniae isolates recovered from diseased pigs with pleuropneumonia from1997 to 2004 was tested for their susceptibility to 11 antimicrobials in a broth microdilution method. All the isolates weresusceptible to florfenicol andmost of themto cephalothin; however, a high rate of resistancewas observed to tetracycline.Abimodalor multimodal distribution of isolates over the MIC range were observed for penicillins, tetracycline, trimethoprim, sulfisoxazoleand nalidixic acid, suggesting the development of acquired resistance. Eight resistance patterns were established, and 21.1%of theisolates were resistant to at least two antimicrobials. In addition, a considerable increase in the resistance to tetracyclines wasobserved during the last decade in Spain, when compared with other A. pleuropneumoniae strains isolated during 1987–1988 PB Elsevier YR 2017 FD 2017-08-01 LK http://hdl.handle.net/10612/6464 UL http://hdl.handle.net/10612/6464 NO Veterinary Microbiology, 2006 NO 5 p. DS BULERIA. Repositorio Institucional de la Universidad de León RD 10-may-2024