TY - JOUR AU - Facultad de Ciencias Biologicas y Ambientales AU - López Ferreras, Lorena AU - Martínez-García, Nicole AU - Maeso Alonso, Laura AU - Martín López, Marta AU - Díez Matilla, Ángela AU - Villoch-Fernández, Javier AU - Alonso-Olivares, Hugo AU - Marqués Martínez, Margarita AU - Marín Vieira, María Carmen AU - Bioquimica y Biologia Molecular DA - 2021/06/06 UR - https://hdl.handle.net/10612/17669 AB - [EN] The p53 family has been widely studied for its role in various physiological and pathological processes. Imbalance of p53 family proteins may contribute to developmental abnormalities and pathologies in humans. This family exerts its functions... LA - eng PB - MDPI KW - Bioquímica KW - Biotecnología KW - Genética KW - p73 isoforms KW - TAp73 KW - DNp73 KW - Mouse embryonic stem cells (mESC) KW - Gene editing KW - Pluripotency KW - Differentiation KW - Cell fate KW - Self-renewal KW - CRISPR/Cas9 TI - Deciphering the Nature of Trp73 Isoforms in Mouse Embryonic Stem Cell Models: Generation of Isoform-Specific Deficient Cell Lines Using the CRISPR/Cas9 Gene Editing System DO - 10.3390/cancers13133182 T2 - Cancers VL - 13 M2 - 3182 ER -