TY - JOUR AU - Facultad de Ciencias Biologicas y Ambientales AU - Morgado Vicente, Cláudia Sofia AU - Diez Payero, Tamara AU - Rodríguez García, Antonio AU - García Barreales, Eva AU - Pedro, Antonio de AU - Santos Beneit, Fernando AU - Aparicio Fernández, Jesús Manuel AU - Microbiologia DA - 2022/07/07 UR - https://hdl.handle.net/10612/17956 AB - [EN] PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from Streptomyces avermitilis. Its mutation drastically abates filipin, but also oligomycin... LA - eng PB - MDPI KW - Biotecnología KW - Streptomyces avermitilis KW - Antibiotics biosynthesis regulation KW - Transcriptional regulation KW - Transcriptomics KW - ΔpteF mutant KW - PAS-LuxR family KW - Antifungal agent KW - Gene regulation KW - Polyene macrolide TI - Modulation of multiple gene clusters’ expression by the PAS-LuxR transcriptional regulator PteF DO - 10.3390/antibiotics11080994 T2 - Antibiotics VL - 11 M2 - 994 ER -