RT info:eu-repo/semantics/article T1 Self-Inhibitory Activity of Trichoderma Soluble Metabolites and Their Antifungal Effects on Fusarium oxysporum A1 Álvarez García, Samuel A1 Mayo Prieto, Sara A1 Gutiérrez Martín, Santiago A1 Casquero Luelmo, Pedro Antonio A2 Fisiologia Vegetal K1 Ingeniería agrícola K1 Self-inhibition K1 Autotoxicity K1 Autoinhibition K1 Membrane Assay K1 Secondary Metabolites K1 Di usible Metabolites K1 Antifungal K1 Fungi K1 Trichoderma K1 Fusarium K1 2417.19 Fisiología Vegetal AB [EN] Self-inhibitory processes are a common feature shared by di erent organisms. One ofthe main mechanisms involved in these interactions regarding microorganisms is the release oftoxic di usible substances into the environment. These metabolites can exert both antimicrobiale ects against other organisms as well as self-inhibitory ones. The in vitro evaluation of thesee ects against other organisms has been widely used to identify potential biocontrol agents againstphytopathogenic microorganisms. In the present study, we performed membrane assays to comparethe self-inhibitory e ects of soluble metabolites produced by several Trichoderma isolates and theirantifungal activity against a phytopathogenic strain of Fusarium oxysporum. The results demonstratedthat Trichoderma spp. present a high self-inhibitory activity in vitro, being a ected in both theirgrowth rate and the macroscopic structure of their colonies. These e ects were highly similar tothose exerted against F. oxysporum in the same conditions, showing no significant di erences inmost cases. Consequently, membrane assays may not be very informative by themselves to assessputative biocontrol capabilities. Therefore, di erent methods, or a combination of antifungal andself-inhibitory experiments, could be a better approach to evaluate the potential biocontrol activity ofmicrobial strains in order to pre-select them for further in vivo trials. PB MDPI LK https://hdl.handle.net/10612/20948 UL https://hdl.handle.net/10612/20948 NO Álvarez-García, S., Mayo-Prieto, S., Gutiérrez, S., & Casquero, P. A. (2020). Self-inhibitory activity of trichoderma soluble metabolites and their antifungal effects on fusarium oxysporum. Journal of Fungi, 6(3), 1-11. https://doi.org/10.3390/JOF6030176 DS BULERIA. Repositorio Institucional de la Universidad de León RD Jul 6, 2024