RT info:eu-repo/semantics/article
T1 Overexpression of the Trichoderma brevicompactum tri5 Gene: Effect on the Expression of the Trichodermin Biosynthetic Genes and on Tomato Seedlings
A1 Tijerino, A. M.
A1 Hermosa, Rosa
A1 Cardoza, Rosa E.
A1 Moraga Galindo, Javier
A1 Gómez Malmierca, Mónica
A1 Aleu Casatejada, Josefina
A1 Collado, Isidro G.
A1 Monte Vázquez, Enrique
A1 Gutiérrez Martín, Santiago
A2 Microbiologia
K1 Biología
K1 Trichothecene
K1 Terpene
K1 Tyrosol
K1 Tri genes
K1 Ergosterol
K1 Gene expression
AB [EN] Trichoderma brevicompactum IBT 40841 produces trichodermin, a trichothecene-type toxin that shares most of the steps of its biosynthesis with harzianum A, another trichothecene produced by several Trichoderma species. The first specific step in the trichothecene biosynthesis is carried out by a terpene cylcase, trichodiene synthase, that catalyzes the conversion of farnesyl pyrophosphate to trichodiene and that is encoded by the tri5 gene. Overexpression of tri5 resulted in increased levels of trichodermin production, but also in an increase in tyrosol and hydroxytyrosol production, two antioxidant compounds that may play a regulatory role in trichothecene biosynthesis, and also in a higher expression of three trichothecene genes, tri4, tri6 and tri10, and of the erg1 gene, which participates in the synthesis of triterpenes. The effect of tri5 overexpression on tomato seedling disease response was also studied
PB MDPI
LK https://hdl.handle.net/10612/21672
UL https://hdl.handle.net/10612/21672
NO Tijerino, A., Hermosa, R., Cardoza, R. E., Moraga, J., Malmierca, M. G., Aleu, J., Collado, I. G., Monte, E., & Gutierrez, S. (2011). Overexpression of the Trichoderma brevicompactum tri5 gene: Effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. Toxins, 3(9), 1220-1232. https://doi.org/10.3390/TOXINS3091220
DS BULERIA. Repositorio Institucional de la Universidad de León
RD Jul 7, 2024