TY  - JOUR 
AU  - Facultad de Ciencias de la Salud
AU  - Liu, Gang
AU  - Casqueiro Blanco, Francisco Javier
AU  - Bañuelos, Óscar
AU  - Cardoza, Rosa E.
AU  - Gutiérrez Martín, Santiago
AU  - Martín Martín, Juan Francisco
AU  - Microbiologia
DA  - 2001/03/03
SN  - 0021-9193
UR  - https://hdl.handle.net/10612/17811
AB  - [EN] Targeted gene disruption efficiency in Acremonium chrysogenum was increased 10-fold by applying the double-marker enrichment technique to this filamentous fungus. Disruption of themecB gene by the double-marker technique was achieved in 5% of the...
LA  - eng
PB  - American Society for Microbiology
KW  - Biología
KW  - Filamentous fungi
KW  - Beta-lactam antibiotics
KW  - Cephalosporin biosynthesis
KW  - Cystathionine-γ-Lyase
TI  - Targeted Inactivation of the mecB Gene, Encoding Cystathionine-γ-Lyase, Shows that the Reverse Transsulfuration Pathway Is Required for High-Level Cephalosporin Biosynthesis inAcremonium chrysogenum C10 but Not for Methionine Induction of the Cephalosporin Genes
DO  - 10.1128/JB.183.5.1765-1772.2001
T2  - Journal of Bacteriology
VL  - 183
M2  - 1765
ER  -