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Título
Melatonin affects red deer spermatozoa motility and physiology in capacitating and non‐capacitating conditions
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
Reproduction in Domestic Animals
Número de la revista
S5
Datos de la obra
Fernández-Alegre, E., Lacalle, E., Soriano-Úbeda, C., Carlos Domínguez, J., Casao, A., & Martínez-Pastor, F. (2022). Melatonin affects red deer spermatozoa motility and physiology in capacitating and non-capacitating conditions. Reproduction in Domestic Animals, 57(S5), 82-85. https://doi.org/10.1111/RDA.14137
Editor
Wiley-Blackwell
Fecha
2022
ISSN
0936-6768
Abstract
[EN] Melatonin affects sperm physiology, possibly through membrane receptors. Effects were tested at low concentrations (1 pM, 100 pM, 10 nM and 1 µM) in red deer epididymal spermatozoa as a model for high-seasonality species. Samples were incubated with melatonin as uncapacitated or capacitating conditions (heparin) and evaluated for motility and physiology (flow cytometry). Most effects occurred at low concentrations (nM-pM), mainly protecting from apoptosis and maintaining acrosomal integrity, suggesting a role for membrane receptors rather than a direct antioxidant effect. Intracellular calcium was not affected, differing from other studies and perhaps because of the epididymal origin. This study supports the relevance of melatonin on sperm physiology and could contribute to the application of reproductive technologies in wild ruminants.
Materia
Palabras clave
Peer review
SI
ID proyecto
- info:eu-repo/grantAgreement/MINECO/Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia/AGL2013-43328-P/ES/METABOLISMO DE LA MELATONINA EN EL TRACTO GENITAL MASCULINO. IMPLICACION DE ESTA HORMONA EN LA CALIDAD SEMINAL Y FISIOLOGIA DE LOS ESPERMATOZOIDES
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