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Título
Plasmonic Biosensors for Single-Molecule Biomedical Analysis
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
Biosensors
Número de la revista
4
Cita Bibliográfica
Mauriz, E., & Lechuga, L. M. (2021). Plasmonic Biosensors for Single-Molecule Biomedical Analysis [Review of Plasmonic Biosensors for Single-Molecule Biomedical Analysis]. Biosensors, 11(4). NLM (Medline). https://doi.org/10.3390/BIOS11040123
Editorial
MDPI
Fecha
2021
Resumen
[EN] The rapid spread of epidemic diseases (i.e., coronavirus disease 2019 (COVID-19)) has contributed
to focus global attention on the diagnosis of medical conditions by ultrasensitive detection
methods. To overcome this challenge, increasing efforts have been driven towards the development
of single-molecule analytical platforms. In this context, recent progress in plasmonic biosensing has
enabled the design of novel detection strategies capable of targeting individual molecules while
evaluating their binding affinity and biological interactions. This review compiles the latest advances
in plasmonic technologies for monitoring clinically relevant biomarkers at the single-molecule
level. Functional applications are discussed according to plasmonic sensing modes based on either
nanoapertures or nanoparticle approaches. A special focus was devoted to new analytical developments
involving a wide variety of analytes (e.g., proteins, living cells, nucleic acids and viruses).
The utility of plasmonic-based single-molecule analysis for personalized medicine, considering
technological limitations and future prospects, is also overviewed
Materia
Palabras clave
Peer review
SI
URI
DOI
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