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Título
Clinical Applications of Visual Plasmonic Colorimetric Sensing
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
Sensors
Número de la revista
21
Datos de la obra
Mauriz, E. (2020). Clinical applications of visual plasmonic colorimetric sensing [Review of Clinical applications of visual plasmonic colorimetric sensing]. Sensors (Switzerland), 20(21), 1-31. MDPI AG. https://doi.org/10.3390/S20216214
Editor
MDPI
Fecha
2020
Abstract
[EN] Colorimetric analysis has become of great importance in recent years to improve the
operationalization of plasmonic-based biosensors. The unique properties of nanomaterials have
enabled the development of a variety of plasmonics applications on the basis of the colorimetric
sensing provided by metal nanoparticles. In particular, the extinction of localized surface plasmon
resonance (LSPR) in the visible range has permitted the exploitation of LSPR colorimetric-based
biosensors as powerful tools for clinical diagnostics and drug monitoring. This review summarizes
recent progress in the biochemical monitoring of clinical biomarkers by ultrasensitive plasmonic
colorimetric strategies according to the distance- or the morphology/size-dependent sensing modes.
The potential of colorimetric nanosensors as point of care devices from the perspective of naked-eye
detection is comprehensively discussed for a broad range of analytes including pharmaceuticals,
proteins, carbohydrates, nucleic acids, bacteria, and viruses such as Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The practical suitability of plasmonic-based colorimetric
assays for the rapid visual readout in biological samples, considering current challenges and future
perspectives, is also reviewed.
Materia
Palabras clave
Peer review
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