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dc.contributor | Facultad de Ciencias de la Salud | es_ES |
dc.contributor.author | Trevissón Redondo, Bibiana | |
dc.contributor.author | Becerro de Bengoa Vallejo, Ricardo | |
dc.contributor.author | Sevillano, David | |
dc.contributor.author | González, Natalia | |
dc.contributor.author | Losa Iglesias, Marta Elena | |
dc.contributor.author | López López, Daniel | |
dc.contributor.author | Alou, Luis | |
dc.contributor.other | Enfermeria | es_ES |
dc.date | 2022 | |
dc.date.accessioned | 2024-02-08T07:59:15Z | |
dc.date.available | 2024-02-08T07:59:15Z | |
dc.identifier.citation | Trevissón, B., Becerro, R., Sevillano, D., González, N., Losa, M. E., López, D., y Alou, L. (2022). Influence of Sexual Dimorphism, Aging, and Differential Cell Capture Efficiency of Blood Separation Systems on the Quality of Platelet-Rich Plasma. Journal of Clinical Medicine, 11(6). https://doi.org/10.3390/JCM11061683 | es_ES |
dc.identifier.other | https://www.mdpi.com/2077-0383/11/6/1683 | es_ES |
dc.identifier.uri | https://hdl.handle.net/10612/18151 | |
dc.description.abstract | [EN] Few studies have checked the impact of the hormonal/immunological dimorphism of patients on the cellular composition of platelet-rich plasma products (PRP). Whole blood (WB) from 26 volunteers was concentrated using a device previously characterized. Platelet and white blood cell (WBC) counts in WB and PRP were compared between genders, and after the population was split into pre (≤50 years)- and post (>50 years)-menopausal ages. In WB, platelet–total WBC densities were comparable in men and women. The phagocytic cell composition differed (p ≤ 0.04). After dividing by ages, phagocytic cell discrepancies were linked to women > 50 years (p ≤ 0.05), and differences emerged in lymphocyte counts (lower in >50 years groups, within and between genders, p ≤ 0.05). In PRP, densities were significantly higher, but the PRP/WB ratios varied according to blood cell (lower for phagocytic cells) and between subjects (more favorable at a lower density of a particular blood cell in WB). This “system compensatory efficiency” reduced/reverted PRP differences in the leukocyte composition between genders/age–sex groups in WB. In PRP, neutrophils were higher in younger men than older women (p < 0.05). WB lymphocyte differences between age–sex groups persisted. Age is a more determining factor than sex in the preparation of PRP. Post-menopause, sexual dimorphism strongly influences the composition of leukocytes, also conditioned by the capture efficiency of the system. | es_ES |
dc.language | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.subject | Enfermería | es_ES |
dc.subject.other | Platelet-rich plasma | es_ES |
dc.subject.other | Leukocytes | es_ES |
dc.subject.other | Sexual dimorphism | es_ES |
dc.subject.other | Aging | es_ES |
dc.subject.other | Blood separation–concentration system | es_ES |
dc.title | Influence of Sexual Dimorphism, Aging, and Differential Cell Capture Efficiency of Blood Separation Systems on the Quality of Platelet-Rich Plasma | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | 10.3390/JCM11061683 | |
dc.description.peerreviewed | SI | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.essn | 2077-0383 | |
dc.journal.title | Journal of Clinical Medicine | es_ES |
dc.volume.number | 11 | es_ES |
dc.issue.number | 6 | es_ES |
dc.page.initial | 1683 | es_ES |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |
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