Mostrar el registro sencillo del ítem
dc.contributor | Facultad de Veterinaria | es_ES |
dc.contributor.author | Argüello Rodríguez, Héctor | |
dc.contributor.author | Guerra, Beatriz | |
dc.contributor.author | Rodríguez, Irene | |
dc.contributor.author | Rubio, Pedro | |
dc.contributor.author | Carvajal Urueña, Ana María | |
dc.contributor.other | Sanidad Animal | es_ES |
dc.date | 2018 | |
dc.date.accessioned | 2024-04-03T11:22:33Z | |
dc.date.available | 2024-04-03T11:22:33Z | |
dc.identifier.citation | Argüello, H., Guerra, B., Rodríguez, I., Rubio, P., & Carvajal, A. (2018). Characterization of antimicrobial resistance determinants and class 1 and class 2 integrons in salmonella enterica spp., multidrug-resistant isolates from pigs. Genes, 9(5). https://doi.org/10.3390/GENES9050256 | es_ES |
dc.identifier.other | https://www.mdpi.com/2073-4425/9/5/256 | es_ES |
dc.identifier.uri | https://hdl.handle.net/10612/19346 | |
dc.description.abstract | [EN] Antimicrobial resistance (AMR) and Salmonella spp., are primary concerns in public health. The present study characterizes the AMR determinants of 62 multi-drug resistant (MDR) Salmonella enterica spp., isolates from swine, which were obtained between 2004-2006, a major source of human salmonellosis. The AMR determinants were investigated by PCR, checking the presence of class 1 and class 2 integrons and 29 resistance genes. Genes sul1, blaTEM1-like, aadA2, tet(A), and dfrA12 were more prevalent (p < 0.05) within the determinants that were checked for each of these antimicrobials. Co-existence of different genes conferring resistance to the same antimicrobial was common. No differences in AMR determinants prevalence were observed between Salmonella Typhimurium and other serovars from the study. Class 1 integrons were detected in 48 of 62 isolates, again with no differences being linked to any serovar. Nine different variable regions were observed, 1000 bp/aadA2-1200 bp/blaPSE-1 (13 isolates) and blaOXA-like/aadA1 (eight isolates) were the most common. Four isolates, including S. Typhimurium (2), Salmonella Bredeney (1), and Salmonella Kapemba (1) harboured a class 2 integron 2300 bp estX-sat2-aadA1. Results from the study highlight the importance of class 1 integrons and certain genes in MDR swine Salmonella isolates. The information is of relevance for monitoring in the forthcoming scope of reduction of antibiotic usage in swine production | es_ES |
dc.language | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Sanidad animal | es_ES |
dc.subject.other | Resistance gene | es_ES |
dc.subject.other | Swine | es_ES |
dc.subject.other | Food-borne pathogen | es_ES |
dc.subject.other | Public health | es_ES |
dc.subject.other | Antibiotic | es_ES |
dc.title | Characterization of Antimicrobial Resistance Determinants and Class 1 and Class 2 Integrons in Salmonella enterica spp., Multidrug-Resistant Isolates from Pigs | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | 10.3390/GENES9050256 | |
dc.description.peerreviewed | SI | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.essn | 2073-4425 | |
dc.journal.title | Genes | es_ES |
dc.volume.number | 9 | es_ES |
dc.issue.number | 5 | es_ES |
dc.page.initial | 256 | es_ES |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |
dc.subject.unesco | 3109 Ciencias Veterinarias | es_ES |
dc.description.project | The authors would like to express their gratitude to the Department Biological Safety, German Federal Institute for Risk Assessment, Berlin, Germany. In particular to all technicians who helped in the laboratory analysis and to the researchers Reiner Helmuth, Bukhard Malorny and Istvan Szabo who provided their advice selflessly. HA is granted by the Spanish Ministry of Economia and Competitividad IJCI-2016-30795 | es_ES |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos [5241]