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Título
Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed.
Part 3: Amprolium
Autor
Facultad/Centro
Área de conocimiento
Título de la revista
EFSA Journal
Número de la revista
10
Cita Bibliográfica
Koutsoumanis, Konstantinos, Ana Allende, Avelino Álvarez Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, and Robert Davies et al. 2021. "Maximum Levels Of Cross‐Contamination For 24 Antimicrobial Active Substances In Non‐Target Feed. Part 3: Amprolium". EFSA Journal 19 (10), Article e6854. doi:10.2903/j.efsa.2021.6854.
Editorial
Wiley Open Access
Fecha
2021
ISSN
1831-4732
Resumen
[EN] The specific concentrations of amprolium in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for amprolium, it was not possible to conclude the assessment. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels of amprolium in feed that showed to have an effect on growth promotion/increased yield were reported. The lack of antibacterial activity at clinically relevant concentrations for amprolium suggests that further studies relating to bacterial resistance are not a priority.
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Peer review
SI
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