RT info:eu-repo/semantics/article T1 Biochemical Profile and Antioxidant Properties of Propolis from Northern Spain A1 Rendueles, Eugenia A1 Mauriz García, Elba A1 Sanz Gómez, José Javier A1 González Paramás, Ana M. A1 Vallejo Pascual, María Eva A1 Adanero Jorge, Félix A1 García Fernández, María del Camino A2 Enfermeria K1 Tecnología de los alimentos K1 Propolis K1 Honeybee products K1 Bioactive compounds K1 Antioxidant properties K1 Food industry K1 3309 Tecnología de Los Alimentos AB [EN] The antioxidant, anti-inflammatory, and antimicrobial characteristics of propolis, a bioactive compound collected from hives, have prompted its use in the food sector in recent times. This study investigated the physicochemical characteristics, phenolic profile, and antioxidant capacity of 31 propolis extracts collected from Northern Spain. The physicochemical composition (resins, waxes, ashes mineral content, and heavy metals) was within the allowable regulatory limits. The analysis of bioactive compounds enabled the identification of 51 constituents: flavonoids (apigenin, catechin, chrysin, quercetin, and pinocembrin) and phenolic acids (caffeic, ferulic, and coumaric). The mean value of total polyphenols was 42.72 ± 13.19 Pinocembrin–Galangin Equivalents/100 g, whereas a range between 1.64 ± 0.04 and 4.95 ± 0.36 Quercetin Equivalents (QE) g/100 g was found for total flavonoids content. The determination of bioactivities revealed significant antioxidant capacity using DPPH (1114.28 ± 10.39 µM Trolox Equivalents and 3487.61 ± 318.66 µM Vitamin C Equivalents). Resin content in propolis samples was positively and significantly correlated with both polyphenols (rho = 0.365; p = 0.043) and flavonoid composition (rho = 0.615; p = 0.000) as well as the antioxidant capacity TEAC DPPH (rho = 0.415; p = 0.020). A multiple regression analysis modeled the correlation between resin composition, flavonoids, and TEAC DPPH values, yielding a significant regression equation (R2 = 0.618; F (2,28) = 22.629; p < 0.000; d = 2.299). Therefore, evaluating physicochemical parameters and biological activities provides a promising framework for predicting propolis’ quality and antioxidant properties, thus suggesting its potential as a functional and bioactive compound forthe food industry. PB MDPI LK https://hdl.handle.net/10612/17893 UL https://hdl.handle.net/10612/17893 NO Rendueles, E., Mauriz, E., Sanz-Gómez, J., González-Paramás, A. M., Vallejo-Pascual, M.-E., Adanero-Jorge, F., y García-Fernández, C. (2023). Biochemical Profile and Antioxidant Properties of Propolis from Northern Spain. Foods, 12(23). https://doi.org/10.3390/FOODS12234337 DS BULERIA. Repositorio Institucional de la Universidad de León RD 19-may-2024