RT info:eu-repo/semantics/article
T1 6-Week Supplementation with Tribulus terrestris L. to Trained Male CrossFit® Athletes on Muscle, Inflammation, and Antioxidant Biomarkers: A Randomized, Single-Blind, Placebo-Controlled Trial
A1 Fernández Lázaro, Diego
A1 Seco Calvo, Jesús Ángel
A1 Pascual Fernández, Jorge
A1 Domínguez Ortega, Carlos
A1 Del Valle Soto, Miguel
A1 Mielgo Ayuso, Juan
A2 Fisioterapia
K1 Fisioterapia
K1 Tribulus terrestris L
K1 Herbal supplementation
K1 CrossFit®
K1 Muscle damage
K1 Inflammation response
K1 Exercise-induced oxidative stress
AB [EN] Tribulus terrestris L. (TT) ingredients have anti-inflammatory and antioxidant activities, but their effects on exercise-induced muscle damage (EIMD) in trained athletes are uncertain. The purpose of this single-blind placebo-controlled trial, in accordance with CONSORT guidelines, was to examine the effect of 6 weeks of TT supplementation on muscle metabolism, inflammation biomarkers, and oxidant status. Thirty trained male CrossFit® athletes were randomly assigned to be supplemented with 770 mg/day of TT (intervention group (IG)) or receive a placebo daily (control group (CG)) for 6 weeks. Muscle damage enzymes, inflammation biomarkers, and Total Antioxidant Status (TAS) were assessed at baseline (T1), 21 days after baseline (T2), and after 42 days (T3). Grace, a Workout of the Day, was measured in T1 and T3. Statistical significance (p < 0.05) was found between IG and CG in Lactate Dehydrogenase (LDH), C-reactive protein (CRP), and TAS levels at the end of the follow-up. Furthermore, TAS levels were significantly (p < 0.05) lower at T2 and T3 relative to baseline in the IG, also LDH and CRP increased significantly (p < 0.05) at T2 and T3 relative to baseline in the CG. No significant (p > 0.05) decreases in muscle damage or inflammation biomarkers were observed, although a slight downward trend was observed after 6 weeks for supplemented athletes. TT supplementation could attenuate the CrossFit® training program-induced oxidative stress, muscle damage, and inflammation which could be due to the natural antioxidant and anti-inflammatory properties of TT.
PB MDPI
SN 1661-7827
LK https://hdl.handle.net/10612/19413
UL https://hdl.handle.net/10612/19413
NO Fernández-Lázaro, D., Seco-Calvo, J., Pascual-Fernández, J., Domínguez-Ortega, C., Del Valle Soto, M., Mielgo-Ayuso, J. (2022) 6-Week Supplementation with Tribulus terrestris L. to Trained Male CrossFit® Athletes on Muscle, Inflammation, and Antioxidant Biomarkers: A Randomized, Single-Blind, Placebo-Controlled Trial.  International Journal of Environmental Research and Public Health 19 (23) https://doi.org/10.3390/ijerph192316158
DS BULERIA. Repositorio Institucional de la Universidad de León
RD 15-jun-2024