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dc.contributor | Facultad de Ciencias de la Salud | es_ES |
dc.contributor.author | Mauriz García, Elba | |
dc.contributor.author | Fernández Vázquez, José P. | |
dc.contributor.author | Díez Flecha, C. | |
dc.contributor.author | Reguero Celada, S. | |
dc.contributor.author | Fernández Villa, Tania | |
dc.contributor.author | Fernández-Somoano, A. | |
dc.contributor.author | Caylà, J.A. | |
dc.contributor.author | Lozano García, J.A. | |
dc.contributor.author | Vázquez Casares, Ana María | |
dc.contributor.author | Martín Sánchez, Vicente | |
dc.contributor.other | Enfermeria | es_ES |
dc.date | 2023 | |
dc.date.accessioned | 2024-01-29T13:37:25Z | |
dc.date.available | 2024-01-29T13:37:25Z | |
dc.identifier.citation | Mauriz, E., Fernández-Vázquez, J. P., Díez-Flecha, C., Reguero-Celada, S., Fernández-Villa, T., Fernández-Somoano, A., Caylà, J. A., Lozano-García, J. A., Vázquez-Casares, A. M., & Martín-Sánchez, V. (2023). Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination. Vaccines, 11(8). https://doi.org/10.3390/VACCINES11081382 | es_ES |
dc.identifier.issn | 2076-393X | |
dc.identifier.uri | https://hdl.handle.net/10612/17888 | |
dc.description.abstract | [EN] Elderly care home residents are particularly vulnerable to COVID-19 due to immunesenescence, pre-existing medical conditions, and the risk of transmission from staff and visitors. This study aimed to describe the outcomes of a COVID-19 outbreak in a long-term care facility for elderly persons following the initial vaccination. A single-center, retrospective, observational design was used to analyze the variables associated with hospitalization and death rate by logistic regression. Adjusted odds ratios (aOR) and their 95% confidence intervals (CI) were calculated. Sixty-eight residents received the first dose of the COVID-19 vaccine. Despite being negative six days after vaccination, the performance of a second test 4 days later revealed 51 positives (75.0%) among residents and 18 among workers (56.3%). A total of 65 of the 68 residents (95.58%) had positive results with symptoms, whereas 34.9% required hospitalization, and 25.8% died. The best-fitting model to explain the distribution of cases reflects three points at the time of infection.. The time from vaccination to symptom onset explains the hospitalization and mortality rates since a day elapsed halves the risk of hospitalization (aOR = 0.57; CI = 0.38−0.75) and the risk of death by a quarter (aOR = 0.74; CI = 0.63−0.88). Nursing homes present an elevated risk of transmission and severity of SARS-CoV-2 infection. Although vaccination reduces the risk of hospitalization and death, extreme prevention and control measures are essential in these institutions despite the high vaccination coverage. | es_ES |
dc.language | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Enfermería | es_ES |
dc.subject.other | Initial vaccination | es_ES |
dc.subject.other | Elderly care home | es_ES |
dc.subject.other | Pre-existing medical conditions | es_ES |
dc.subject.other | Nursing home | es_ES |
dc.subject.other | Vaccination coverage | es_ES |
dc.title | Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | 10.3390/VACCINES11081382 | |
dc.description.peerreviewed | SI | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.journal.title | Vaccines | es_ES |
dc.volume.number | 11 | es_ES |
dc.issue.number | 8 | es_ES |
dc.page.initial | 1382 | es_ES |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |
dc.subject.unesco | 3212 Salud Publica | es_ES |
dc.subject.unesco | 3202 Epidemiología | es_ES |
dc.subject.unesco | 3205 Medicina Interna | es_ES |
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