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Título
The pharmacokinetics and metabolism of ivermectin in domestic animal species
Autor
Facultad/Centro
Área de conocimiento
Cita Bibliográfica
The Veterinary Journal, 2009, n. 179
Editorial
Elsevier
Fecha
2009-07-17
Resumen
The pharmacokinetic properties of drugs are closely related to their pharmacological efficacy. The kinetics of ivermectin are characterised,
in general terms, by a slow absorption process, a broad distribution in the organism, low metabolism, and slow excretion. The
kinetics vary according to the route of administration, formulation, animal species, body condition, age, and physiological status, all of
which contribute to differences in drug efficacy. Characterisation of ivermectin kinetics can be used to predict and optimise the value of
the parasiticide effects and to design programmes for parasite control. This article reviews the pharmacokinetics of ivermectin in several
domestic animal species.
Materia
Palabras clave
Peer review
SI
URI
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