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    Citas

    Título
    Differential Behavior Between Isolated and Aggregated Rabbit Auricular Chondrocytes on Plastic Surfaces
    Autor
    Villar Suárez, María VegaAutoridad BuleriaORCID
    Calles-Venal, I.
    Bravo, G.
    Fernández Álvarez, José GabrielAutoridad BuleriaORCID
    Fernández-Caso, M.
    Villar-Lacilla, J. M.
    Facultad/Centro
    Facultad de Ciencias Biologicas y Ambientales
    Área de conocimiento
    Bioquimica y Biologia Molecular
    Datos de la obra
    Journal of Biomedicine and Biotechnology, 2004, n. 2
    Editor
    Hindawi Publishing Corporation
    Fecha
    2004-01-23
    Abstract
    A knowledge of the behavior of chondrocytes in culture is relevant for tissue engineering. Chondrocytes dedifferentiate 10 a fibroblast· like phenotype on plastic surfaces. Dedifferentiation is reversible if these cells are then cultured in suspension. In this report a descrip· tion is given of how when chondrocyte aggregates formed in suspension are next seeded on plastic, most of them attach as round or polygonal cells. This morphological differentiation, with synthesis of type II collagen, is stable for long culture periods. This sim· pie method can be of use as a model for studies of chondrocyte behavior on plastic. The results indicate that in addition to culture conditions, such as cell isolation method or cell density, chondrocyte behavior on plastic depends on the presence of aggregates
    Materia
    Bioquímica
    Biotecnología
    Palabras clave
    Auricular Chondrocytes
    Plastic Surfaces
    Behavior
    Rabbits
    Peer review
    SI
    URI
    http://hdl.handle.net/10612/6447
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